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Nicotine addiction that occurs with e-cigarette use may lead to a transition to the use of combustible tobacco products, such as cigarettes or little cigars

Reduced respiratory symptoms, such as coughing, wheezing and shortness of breath

Engaging in regular physical activity at the levels recommended by the Centers for Disease Control and Prevention (CDC) can reduce the risk of nine different types of cancer, with research indicating that over 46,000 US cancer cases annually could potentially be avoided if everyone met the recommended CDC guidelines for physical activity (see Sidebar 11 ) (248)(249)

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